{"id":3555,"date":"2021-02-08T12:29:12","date_gmt":"2021-02-08T12:29:12","guid":{"rendered":"https:\/\/www.thervacb.eu\/equip\/soci-aop\/"},"modified":"2025-07-22T09:16:41","modified_gmt":"2025-07-22T08:16:41","slug":"soci-aop","status":"publish","type":"page","link":"https:\/\/www.thervacb.eu\/ca\/equip\/soci-aop\/","title":{"rendered":"Soci AOP"},"content":{"rendered":"

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\"Hospital<\/a><\/p>\n

[\/et_pb_map_pin_extended][et_pb_map_pin_extended title=”CTC North” pin_address=”Martinistra\u00dfe 64, 20251 Hamburg, Deutschland” pin_address_lat=”53.5898297″ pin_address_lng=”9.9736084″ pin_fill_color=”#2d788c” pin_stroke_color=”#06423a” pin_circle_color=”#ffffff” _builder_version=”4.21.0″ global_colors_info=”{}”]<\/p>\n

\"CTC<\/a><\/p>\n

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\"Fundaci\u00f3<\/a><\/p>\n

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\"Helmholtz-Zentrum<\/a><\/p>\n

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\"MHH\"<\/a><\/p>\n

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\"NIMR-Mbeya<\/a><\/p>\n

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\"\u6c64\u59c6\"<\/a> <\/p>\n

[\/et_pb_map_pin_extended][et_pb_map_pin_extended title=”UNIVERSITY COLLEGE LONDON (UCL)” pin_address=”GOWER STREET, WC1E 6BT London” pin_address_lat=”51.5233687″ pin_address_lng=”-0.135766″ pin_fill_color=”#2d788c” pin_stroke_color=”#06423a” pin_circle_color=”#ffffff” _builder_version=”4.21.0″ global_colors_info=”{}”]<\/p>\n

\"UNIVERSITY<\/a><\/p>\n

[\/et_pb_map_pin_extended][et_pb_map_pin_extended title=”ARTTIC SAS” pin_address=”58a Rue du Dessous des Berges, 75013 Paris, Frankreich” pin_address_lat=”48.827405″ pin_address_lng=”2.3743052″ pin_fill_color=”#2d788c” pin_stroke_color=”#06423a” pin_circle_color=”#ffffff” _builder_version=”4.21.0″ global_colors_info=”{}”]<\/p>\n

\"\"<\/a><\/p>\n

[\/et_pb_map_pin_extended][et_pb_map_pin_extended title=”Klinikum Rechts der Isar der Technischen Universit\u00e4t M\u00fcnchen” pin_address=”H\u00f6rsaal A, Klinikum rechts der Isar, Ismaninger Str. 22, 81675 M\u00fcnchen, Deutschland” pin_address_lat=”48.1360041″ pin_address_lng=”11.5997829″ pin_fill_color=”#2d788c” pin_stroke_color=”#06423a” pin_circle_color=”#ffffff” _builder_version=”4.21.0″ global_colors_info=”{}”]<\/p>\n

\"Klinikum<\/a><\/p>\n

[\/et_pb_map_pin_extended][et_pb_map_pin_extended title=”University Medical Center Hamburg-Eppendorf, I. Department of Internal Medicine” pin_address=”Martinistra\u00dfe 52, 20251 Hamburg, Deutschland” pin_address_lat=”53.5902421″ pin_address_lng=”9.9785922″ pin_fill_color=”#2d788c” pin_stroke_color=”#06423a” pin_circle_color=”#ffffff” _builder_version=”4.21.0″ global_colors_info=”{}”]<\/p>\n

\"University<\/a><\/p>\n

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\"Universit\u00e4t<\/a><\/p>\n

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\"Barts<\/a><\/p>\n

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\"ARTTIC<\/a><\/p>\n

[\/et_pb_map_pin_extended][\/et_pb_map_fullwidth_extended][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row column_structure=”3_4,1_4″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”3_4″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ custom_padding=”0px|||||” global_colors_info=”{}”]<\/p>\n

Azienda Ospedaliero-
Universitaria di Parma<\/strong><\/h1>\n

<\/h2>\n

Informaci\u00f3 general<\/h2>\n

El Azienda Ospedaliero-Universitaria de Parma<\/strong> va n\u00e9ixer a l\u2019\u00e8poca medieval. Es tracta d\u2019una estructura altament especialitzada que integra funcions universit\u00e0ries i hospital\u00e0ries, que opera en els camps de l\u2019assist\u00e8ncia, la investigaci\u00f3 i la doc\u00e8ncia. S\u2019organitza en 6 departaments, s\u2019estructura al voltant de 28 edificis i compta amb un TechnoPole l\u00edder en investigaci\u00f3 (Core-Lab), que inclou 7 laboratoris amb equips d\u2019avantguarda.<\/p>\n

L\u2019hospital t\u00e9 1047 llits, 3.850 unitats de personal i unes 171 unitats de professorat.<\/p>\n

En concret, el Unitat de Malalties Infeccioses i Hepatologia a Parma<\/strong> \u00e9s un centre nacional de refer\u00e8ncia per al tractament cl\u00ednic d\u2019infeccions v\u00edriques cr\u00f2niques, en particular l\u2019hepatitis per VHB i VHC, que atrau un gran nombre de pacients a nivell regional i interregional. S’organitza amb dues sales separades (31 llits), un hospital de dia (9 llits), un ambulatori per a infeccions per virus de l’hepatitis i instal\u00b7lacions de laboratori. La unitat est\u00e0 totalment equipada per a bi\u00f2psies d\u2019agulla hep\u00e0tica, ecografia diagn\u00f2stica i intervencionista i per a estudis de biologia immunol\u00f2gica i molecular. Les instal\u00b7lacions hospital\u00e0ries de tota l\u2019Azienda Ospedaliero-Universitaria de Parma tamb\u00e9 estan disponibles per al Dr. Boni, inclosos els laboratoris cl\u00ednics i d\u2019investigaci\u00f3 centralitzats i tot l\u2019espectre de serveis cl\u00ednics consultius.<\/p>\n

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Azienda Ospedaliero-Universitaria di Parma<\/strong><\/strong><\/p>\n

Via Gramsci 14
43126 Parma
It\u00e0lia<\/p>\n

www.ao.pr.it<\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ global_colors_info=”{}”]<\/p>\n

Rol a TherVacB<\/h2>\n

En aquest projecte, l\u2019Azienda Ospedaliero-Universitaria de Parma contribuir\u00e0 al seguiment immunol\u00f2gic de TherVacB, en particular a l\u2019estudi de respostes adaptatives espec\u00edfiques del VHB, i ajudar\u00e0 a establir nous biomarcadors per avaluar i predir l\u2019efecte d\u2019una nova ter\u00e0pia immune. La tasca espec\u00edfica de la Unitat a Parma ser\u00e0 caracteritzar perfils fenot\u00edpics, metab\u00f2lics, transcripcionals i funcionals de c\u00e8l\u00b7lules T CD8 espec\u00edfiques del VHB. A m\u00e9s, l\u2019Hospital Universitari de Parma contribuir\u00e0 al reclutament de pacients amb hepatitis B cr\u00f2nica per tractar-los amb TherVacB.<\/p>\n

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Personal del projecte<\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_image src=”https:\/\/www.thervacb.eu\/wp-content\/uploads\/Parma-Team.jpg” _builder_version=”4.16″ border_radii=”off|10px|10px|10px|10px” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” _builder_version=”4.16″ custom_padding=”0px|||||” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_team_member name=”Carolina Boni” position=”Metge i professor adjunt ” module_class=”noimage” _builder_version=”4.16″ header_text_align=”center” position_text_align=”center” position_line_height=”2em” text_orientation=”left” custom_padding=”20px|20px|20px|20px|false|false” border_radii=”on|10px|10px|10px|10px” box_shadow_style=”preset1″ global_colors_info=”{}” transform_styles__hover_enabled=”on|hover” transform_scale__hover_enabled=”on|hover” transform_translate__hover_enabled=”on|desktop” transform_rotate__hover_enabled=”on|desktop” transform_skew__hover_enabled=”on|desktop” transform_origin__hover_enabled=”on|desktop” transform_scale__hover=”105%|105%” custom_css_member_image_last_edited=”on|desktop”]<\/p>\n

La seva investigaci\u00f3 se centra principalment en la caracteritzaci\u00f3 dels mecanismes immunitaris responsables de la persist\u00e8ncia viral i el dany hep\u00e0tic en la infecci\u00f3 cr\u00f2nica del VHB amb l’objectiu final de desenvolupar noves estrat\u00e8gies immunoter\u00e0piques per a pacients infectats cr\u00f2nicament.<\/span><\/p>\n

[\/et_pb_team_member][et_pb_team_member name=”Diletta Laccabue” position=”Coordinador de Recerca Cl\u00ednica a la Unitat de Malalties Infeccioses i Hepatologia” module_class=”noimage” _builder_version=”4.16″ header_text_align=”center” position_text_align=”center” position_line_height=”2em” text_orientation=”left” custom_padding=”20px|20px|20px|20px|false|false” border_radii=”on|10px|10px|10px|10px” box_shadow_style=”preset1″ global_colors_info=”{}” transform_styles__hover_enabled=”on|hover” transform_scale__hover_enabled=”on|hover” transform_translate__hover_enabled=”on|desktop” transform_rotate__hover_enabled=”on|desktop” transform_skew__hover_enabled=”on|desktop” transform_origin__hover_enabled=”on|desktop” transform_scale__hover=”105%|105%” custom_css_member_image_last_edited=”on|desktop”]<\/p>\n

Ella d\u00f3na suport al personal cl\u00ednic de Barcelona<\/span> la conducci\u00f3, segons ICH-GCP, de la fase II, III, IV i estudis cl\u00ednics observacionals, amb \u00e0nim de lucre i sense \u00e0nim de lucre, nacionals i internacionals.<\/span><\/p>\n

[\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_team_member name=”Carlo Ferrari” position=”Professor i Director de la Unitat de Malalties Infeccioses i Hepatologia i Laboratori d\u2019Immunopatologia Viral ” module_class=”noimage” _builder_version=”4.16″ header_text_align=”center” position_text_align=”center” position_line_height=”2em” text_orientation=”left” custom_padding=”20px|20px|20px|20px|false|false” border_radii=”on|10px|10px|10px|10px” box_shadow_style=”preset1″ global_colors_info=”{}” transform_styles__hover_enabled=”on|hover” transform_scale__hover_enabled=”on|hover” transform_translate__hover_enabled=”on|desktop” transform_rotate__hover_enabled=”on|desktop” transform_skew__hover_enabled=”on|desktop” transform_origin__hover_enabled=”on|desktop” transform_scale__hover=”105%|105%” custom_css_member_image_last_edited=”on|desktop”]<\/p>\n

La seva carrera cient\u00edfica general s\u2019ha centrat en l\u2019estudi de la immunopatog\u00e8nesi de l\u2019hepatitis viral amb l\u2019objectiu final de desenvolupar noves estrat\u00e8gies terap\u00e8utiques per<\/span> infeccions v\u00edriques cr\u00f2niques. <\/p>\n

[\/et_pb_team_member][et_pb_team_member name=”Amalia Penna” position=”Bi\u00f2leg” module_class=”noimage” _builder_version=”4.16″ header_text_align=”center” position_text_align=”center” position_line_height=”2em” text_orientation=”left” custom_padding=”20px|20px|20px|20px|false|false” border_radii=”on|10px|10px|10px|10px” box_shadow_style=”preset1″ global_colors_info=”{}” transform_styles__hover_enabled=”on|hover” transform_scale__hover_enabled=”on|hover” transform_translate__hover_enabled=”on|desktop” transform_rotate__hover_enabled=”on|desktop” transform_skew__hover_enabled=”on|desktop” transform_origin__hover_enabled=”on|desktop” transform_scale__hover=”105%|105%” custom_css_member_image_last_edited=”on|desktop”]<\/p>\n

Se centrar\u00e0 en el c<\/span> haracteritzaci\u00f3 dels mecanismes responsables de la falta de resposta de les c\u00e8l\u00b7lules T espec\u00edfiques del VHB i del VHC en pacients amb infecci\u00f3 cr\u00f2nica i de la recuperaci\u00f3 funcional de les c\u00e8l\u00b7lules immunes durant la ter\u00e0pia antiviral<\/span> .<\/p>\n

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