{"id":3676,"date":"2021-02-08T12:30:24","date_gmt":"2021-02-08T12:30:24","guid":{"rendered":"https:\/\/www.thervacb.eu\/equip\/soci-hzi\/"},"modified":"2025-10-23T08:10:12","modified_gmt":"2025-10-23T07:10:12","slug":"soci-hzi","status":"publish","type":"page","link":"https:\/\/www.thervacb.eu\/ca\/equip\/soci-hzi\/","title":{"rendered":"Soci HZI"},"content":{"rendered":"<p>[et_pb_section fb_built=\u00bb1&#8243; fullwidth=\u00bbon\u00bb admin_label=\u00bbMap\u00bb _builder_version=\u00bb4.9.0&#8243; da_disable_devices=\u00bboff|off|off\u00bb global_module=\u00bb539&#8243; saved_tabs=\u00bball\u00bb global_colors_info=\u00bb{}\u00bb da_is_popup=\u00bboff\u00bb da_exit_intent=\u00bboff\u00bb da_has_close=\u00bbon\u00bb da_alt_close=\u00bboff\u00bb da_dark_close=\u00bboff\u00bb da_not_modal=\u00bbon\u00bb da_is_singular=\u00bboff\u00bb da_with_loader=\u00bboff\u00bb da_has_shadow=\u00bbon\u00bb][et_pb_map_fullwidth_extended address=\u00bbParis, France\u00bb zoom_level=\u00bb2&#8243; address_lat=\u00bb43.762201679538&#8243; 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pin_address_lng=\u00bb11.5685941&#8243; pin_fill_color=\u00bb#2d788c\u00bb pin_stroke_color=\u00bb#06423a\u00bb pin_circle_color=\u00bb#ffffff\u00bb _builder_version=\u00bb4.21.0&#8243; global_colors_info=\u00bb{}\u00bb]<\/p>\n<p><a href=\"https:\/\/www.thervacb.eu\/ca\/equip\/soci-tum\/\" title=\"Technische Universit\u00e4t M\u00fcnchen\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.thervacb.eu\/wp-content\/uploads\/tum-logo.png\" alt=\"\u6c64\u59c6\" class=\"wp-image-768 size-full\" width=\"200\" height=\"67\"><\/a> <\/p>\n<p>[\/et_pb_map_pin_extended][et_pb_map_pin_extended title=\u00bbUNIVERSITY COLLEGE LONDON (UCL)\u00bb pin_address=\u00bbGOWER STREET, WC1E 6BT London\u00bb pin_address_lat=\u00bb51.5233687&#8243; pin_address_lng=\u00bb-0.135766&#8243; pin_fill_color=\u00bb#2d788c\u00bb pin_stroke_color=\u00bb#06423a\u00bb pin_circle_color=\u00bb#ffffff\u00bb _builder_version=\u00bb4.21.0&#8243; global_colors_info=\u00bb{}\u00bb]<\/p>\n<p><a href=\"https:\/\/www.thervacb.eu\/ca\/equip\/soci-ucl\/\" title=\"UNIVERSITY COLLEGE LONDON (UCL)\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.thervacb.eu\/wp-content\/uploads\/ucl-logo.png\" alt=\"UNIVERSITY COLLEGE LONDON (UCL)\" class=\"wp-image-770 size-full\" width=\"200\" height=\"59\"><\/a><\/p>\n<p>[\/et_pb_map_pin_extended][et_pb_map_pin_extended title=\u00bbKlinikum Rechts der Isar der Technischen Universit\u00e4t M\u00fcnchen\u00bb pin_address=\u00bbH\u00f6rsaal A, Klinikum rechts der Isar, Ismaninger Str. 22, 81675 M\u00fcnchen, Deutschland\u00bb pin_address_lat=\u00bb48.1360041&#8243; 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global_colors_info=\u00bb{}\u00bb]<a href=\"https:\/\/www.thervacb.eu\/team\/partner-aop-new\/\" title=\"Azienda Ospedaliero- Universitaria di Parma\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-520 aligncenter size-medium\" src=\"https:\/\/www.thervacb.eu\/wp-content\/uploads\/logo-azienda-ospedaliero-universitaria-di-parma-1-400x82.png\" alt=\"Azienda Ospedaliero- Universitaria di Parma\" width=\"200\" height=\"41\" title=\"Azienda Ospedaliero- Universitaria di Parma\" srcset=\"https:\/\/www.thervacb.eu\/wp-content\/uploads\/logo-azienda-ospedaliero-universitaria-di-parma-1-400x83.png 400w, https:\/\/www.thervacb.eu\/wp-content\/uploads\/logo-azienda-ospedaliero-universitaria-di-parma-1.png 406w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/a>[\/et_pb_map_pin_extended][et_pb_map_pin_extended title=\u00bbUniversit\u00e4tsklinikum Leipzig\u00bb pin_address=\u00bbRitterstra\u00dfe 26, 04109 Leipzig, Deutschland\u00bb pin_address_lat=\u00bb51.3412809&#8243; pin_address_lng=\u00bb12.3802676&#8243; pin_fill_color=\u00bb#2d788c\u00bb pin_stroke_color=\u00bb#06423a\u00bb pin_circle_color=\u00bb#ffffff\u00bb _builder_version=\u00bb4.25.0&#8243; global_colors_info=\u00bb{}\u00bb]<a title=\"Universit\u00e4tsklinikum Leipzig\" href=\"https:\/\/www.thervacb.eu\/ca\/equip\/soci-ulei\/\"><img decoding=\"async\" class=\"alignnone wp-image-4300 size-medium\" title=\"Universit\u00e4tsklinikum Leipzig\" src=\"https:\/\/www.thervacb.eu\/wp-content\/uploads\/university-leipzig.png\" alt=\"Universit\u00e4tsklinikum Leipzig\" width=\"200\"><\/a>[\/et_pb_map_pin_extended][et_pb_map_pin_extended title=\u00bbBarts Health NHS Trust\u00bb pin_address=\u00bbCo-operative Bank Plc, 9 Prescot St, Whitechapel, London E1 8AZ, Vereinigtes K\u00f6nigreich\u00bb zoom_level=\u00bb5&#8243; pin_address_lat=\u00bb51.5115034&#8243; pin_address_lng=\u00bb-0.0706499&#8243; pin_fill_color=\u00bb#2d788c\u00bb pin_stroke_color=\u00bb#06423a\u00bb pin_circle_color=\u00bb#ffffff\u00bb _builder_version=\u00bb4.21.0&#8243; 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pin_address_lng=\u00bb11.5760781&#8243; pin_fill_color=\u00bb#2d788c\u00bb pin_stroke_color=\u00bb#06423a\u00bb pin_circle_color=\u00bb#ffffff\u00bb _builder_version=\u00bb4.25.0&#8243; global_colors_info=\u00bb{}\u00bb]<a title=\"PNO Innovation GmbH\" href=\"https:\/\/www.thervacb.eu\/de\/team\/pno-innovation\/\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-4300 size-medium\" title=\"PNO Innovation GmbH\" src=\"https:\/\/www.thervacb.eu\/wp-content\/uploads\/PNO-Innovation-logo.png\" alt=\"PNO Innovation GmbH\" width=\"200\" height=\"28\"><\/a>[\/et_pb_map_pin_extended][et_pb_map_pin_extended title=\u00bbSocraTec R&#038;D GmbH\u00bb pin_address=\u00bbIm Setzling 35, 61440 Oberursel (Taunus), Deutschland\u00bb pin_address_lat=\u00bb50.1968591&#8243; pin_address_lng=\u00bb8.5860136&#8243; pin_fill_color=\u00bb#2d788c\u00bb pin_stroke_color=\u00bb#06423a\u00bb pin_circle_color=\u00bb#ffffff\u00bb _builder_version=\u00bb4.25.0&#8243; display_conditions=\u00bbW10=\u00bb global_colors_info=\u00bb{}\u00bb]<a title=\"SocraTec R&amp;D GmbH\" href=\"https:\/\/www.thervacb.eu\/team\/socratech\/\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-4300 size-medium\" title=\"SocraTec R&amp;D GmbH\" src=\"https:\/\/www.thervacb.eu\/wp-content\/uploads\/socratec-and-r-d-logo.svg\" alt=\"SocraTec R&amp;D GmbH\" width=\"200\" height=\"47\"><\/a>[\/et_pb_map_pin_extended][et_pb_map_pin_extended title=\u00bbFrankfurt University Hospital\u00bb pin_address=\u00bbTheodor-Stern-Kai 7, 60596 Frankfurt am Main, Deutschland\u00bb pin_address_lat=\u00bb50.095683&#8243; pin_address_lng=\u00bb8.6595022&#8243; pin_fill_color=\u00bb#2d788c\u00bb pin_stroke_color=\u00bb#06423a\u00bb pin_circle_color=\u00bb#ffffff\u00bb _builder_version=\u00bb4.25.0&#8243; display_conditions=\u00bbW10=\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n<p><a title=\"Frankfurt University Hospital\" href=\"https:\/\/www.thervacb.eu\/ca\/equip\/soci-guf\/\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-4300 size-medium\" title=\"Frankfurt University Hospital\" src=\"https:\/\/www.thervacb.eu\/wp-content\/uploads\/frankfurt-university-hospital-logo.png\" alt=\"Frankfurt University Hospital\" width=\"183\" height=\"100\"><\/a><\/p>\n<p>[\/et_pb_map_pin_extended][\/et_pb_map_fullwidth_extended][\/et_pb_section][et_pb_section fb_built=\u00bb1&#8243; _builder_version=\u00bb4.16&#8243; da_disable_devices=\u00bboff|off|off\u00bb global_colors_info=\u00bb{}\u00bb da_is_popup=\u00bboff\u00bb da_exit_intent=\u00bboff\u00bb da_has_close=\u00bbon\u00bb da_alt_close=\u00bboff\u00bb da_dark_close=\u00bboff\u00bb da_not_modal=\u00bbon\u00bb da_is_singular=\u00bboff\u00bb da_with_loader=\u00bboff\u00bb da_has_shadow=\u00bbon\u00bb][et_pb_row column_structure=\u00bb3_4,1_4&#8243; _builder_version=\u00bb4.16&#8243; global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb3_4&#8243; _builder_version=\u00bb4.16&#8243; global_colors_info=\u00bb{}\u00bb][et_pb_text _builder_version=\u00bb4.16&#8243; global_colors_info=\u00bb{}\u00bb]<\/p>\n<h1><strong>Helmholtz-Zentrum f\u00fcr Infektionsforschung GmbH (HZI)<br \/><\/strong><\/h1>\n<h2><\/h2>\n<h2>Informaci\u00f3 general<\/h2>\n<p>El Helmholtz Center for Infection Research (HZI) de Braunschweig \u00e9s un centre d&#8217;investigaci\u00f3 finan\u00e7at amb fons p\u00fablics amb m\u00e9s de 900 empleats i un pressupost anual d&#8217;aproximadament 70 milions d&#8217;euros, aix\u00ed com fons externs d&#8217;aproximadament 16 milions d&#8217;euros procedents de programes de suport nacionals i internacionals i de la ind\u00fastria. El focus de les seves activitats es troba en el camp de la infecci\u00f3. La missi\u00f3 de l\u2019HZI \u00e9s afrontar els reptes socials de les malalties infeccioses investigant els seus mecanismes fonamentals de patog\u00e8nesi, amb l\u2019objectiu de derivar enfocaments innovadors per a la seva prevenci\u00f3, diagn\u00f2stic i ter\u00e0pia. L\u2019HZI tamb\u00e9 \u00e9s membre del Centre Alemany de Recerca en Infeccions (35 institucions d\u2019investigaci\u00f3 ubicades a set llocs), amb l\u2019oficina de direcci\u00f3 situada al campus HZI.<\/p>\n<p>Les activitats cient\u00edfiques del Departament de Vaccinologia i Microbiologia Aplicada, dirigit pel professor Carlos A. Guzm\u00e1n, estan dedicades a:<\/p>\n<ul>\n<li>aclarir els mecanismes de resposta de l\u2019hoste a la infecci\u00f3 i la vacunaci\u00f3,<\/li>\n<li>desenvolupament de nous sistemes de distribuci\u00f3 d &#8216;antig\u00e8nics i adjuvants, i<\/li>\n<li>desenvolupament i validaci\u00f3 de vacunes contra malalties infeccioses espec\u00edfiques.<\/li>\n<\/ul>\n<p> Aix\u00f2 inclou:<\/p>\n<p>establir sistemes d\u2019administraci\u00f3 basats en nanotransportants i adjuvants,<\/p>\n<ul>\n<li>desenvolupament de vacunes contra pat\u00f2gens espec\u00edfics (<em> per exemple.<\/em> virus de l\u2019hepatitis B i C, virus de la grip,<em> Trypanosoma cruzi<\/em> ),<\/li>\n<li>generar enfocaments avan\u00e7ats de monitoratge immune per avaluar respostes immunes innates i adaptatives despr\u00e9s de la vacunaci\u00f3 en models precl\u00ednics i humans,<\/li>\n<li>avaluar les respostes a les vacunes en humans i<\/li>\n<li>identificar signatures immunol\u00f2giques genot\u00edpiques i fenot\u00edpiques inicials que prediuin una vacunaci\u00f3 reeixida.<\/li>\n<\/ul>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_4&#8243; _builder_version=\u00bb4.16&#8243; background_enable_color=\u00bboff\u00bb use_background_color_gradient=\u00bbon\u00bb background_color_gradient_stops=\u00bbrgba(0,0,0,0) 0%|rgba(92,189,217,0.25) 100%\u00bb background_color_gradient_start=\u00bbrgba(0,0,0,0)\u00bb background_color_gradient_end=\u00bbrgba(92,189,217,0.25)\u00bb background_enable_image=\u00bboff\u00bb background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb custom_padding=\u00bb10px|10px|10px|10px|false|false\u00bb border_radii=\u00bbon|10px|10px|10px|10px\u00bb border_width_all=\u00bb2px\u00bb border_color_all=\u00bb#5cbdd9&#8243; global_colors_info=\u00bb{}\u00bb][et_pb_image src=\u00bbhttps:\/\/www.thervacb.eu\/wp-content\/uploads\/helmholtz.svg\u00bb _builder_version=\u00bb4.25.0&#8243; hover_enabled=\u00bb0&#8243; global_colors_info=\u00bb{}\u00bb alt=\u00bbHelmholtz\u00bb title_text=\u00bbhelmholtz\u00bb max_width=\u00bb300px\u00bb sticky_enabled=\u00bb0&#8243;][\/et_pb_image][et_pb_text _builder_version=\u00bb4.16&#8243; max_width=\u00bb100%\u00bb module_alignment=\u00bbleft\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n<p><strong><\/strong><strong>Helmholtz-Zentrum f\u00fcr Infektionsforschung GmbH<\/strong><\/p>\n<p>Inhoffenstr. 7<br \/>38124 Braunschweig<br \/>Germany<\/p>\n<p><a href=\"http:\/\/www.helmholtz-hzi.de\/en\" target=\"_blank\" rel=\"noopener noreferrer\" title=\"Helmholtz Zentrum f\u00fcr Infektionsforschung\">www.helmholtz-hzi.de\/ca<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\u00bb4.16&#8243; global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4&#8243; _builder_version=\u00bb4.16&#8243; global_colors_info=\u00bb{}\u00bb][et_pb_text _builder_version=\u00bb4.16&#8243; global_colors_info=\u00bb{}\u00bb]<\/p>\n<h2>Rol a TherVacB<\/h2>\n<p>El professor Guzm\u00e1n i el seu grup de l\u2019HZI han estudiat i desenvolupat c-di-AMP com a potent adjuvant novell i han patentat el seu \u00fas per a la vacunaci\u00f3 terap\u00e8utica i profil\u00e0ctica. Estudis de prova de principi de no GLP van demostrar que c-di-AMP va ser capa\u00e7 de millorar tant les respostes immunes humorals com les cel\u00b7lulars als ant\u00edgens relacionats amb la malaltia<em> Streptococcus pyogenes<\/em> , VHB, VHC, virus de la grip i<em> Trypanosoma cruzi<\/em> despr\u00e9s de la vacunaci\u00f3 parenteral o de la mucosa. L\u2019HZI no nom\u00e9s contribuir\u00e0 amb c-di-AMP al projecte TherVacB, sin\u00f3 que tamb\u00e9 aportar\u00e0 la seva experi\u00e8ncia per ajudar a preparar els dossiers d\u2019assaigs cl\u00ednics, obtenir l\u2019aprovaci\u00f3 reguladora i desenvolupar el pla de gesti\u00f3 de dades, aix\u00ed com donar suport a la recollida i gesti\u00f3 de dades durant l\u2019assaig cl\u00ednic.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb||0px|||\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4&#8243; _builder_version=\u00bb4.16&#8243; global_colors_info=\u00bb{}\u00bb][et_pb_text _builder_version=\u00bb4.16&#8243; global_colors_info=\u00bb{}\u00bb]<\/p>\n<h2>Personal del projecte<\/h2>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\u00bb1_3,1_3,1_3&#8243; make_equal=\u00bbon\u00bb _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb0px|||||\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb1_3&#8243; _builder_version=\u00bb4.16&#8243; global_colors_info=\u00bb{}\u00bb][et_pb_team_member name=\u00bbCarlos Alberto Guzm\u00e1n\u00bb position=\u00bbCap del departament de vacunologia i microbiologia aplicada\u00bb image_url=\u00bbhttps:\/\/www.thervacb.eu\/wp-content\/uploads\/HZI_Carlos-Guzman.jpg\u00bb _builder_version=\u00bb4.16&#8243; header_text_align=\u00bbcenter\u00bb position_text_align=\u00bbcenter\u00bb position_line_height=\u00bb2em\u00bb text_orientation=\u00bbleft\u00bb custom_padding=\u00bb20px|20px|20px|20px|false|false\u00bb border_radii=\u00bbon|10px|10px|10px|10px\u00bb box_shadow_style=\u00bbpreset1&#8243; global_colors_info=\u00bb{}\u00bb transform_styles__hover_enabled=\u00bbon|hover\u00bb transform_scale__hover_enabled=\u00bbon|hover\u00bb transform_translate__hover_enabled=\u00bbon|desktop\u00bb transform_rotate__hover_enabled=\u00bbon|desktop\u00bb transform_skew__hover_enabled=\u00bbon|desktop\u00bb transform_origin__hover_enabled=\u00bbon|desktop\u00bb transform_scale__hover=\u00bb105%|105%\u00bb custom_css_member_image_last_edited=\u00bbon|desktop\u00bb]<\/p>\n<p style=\"text-align: center;\">Gesti\u00f3 cient\u00edfica, <br \/>Vacunologia i Immunologia<\/p>\n<p>[\/et_pb_team_member][\/et_pb_column][et_pb_column type=\u00bb1_3&#8243; _builder_version=\u00bb4.16&#8243; global_colors_info=\u00bb{}\u00bb][et_pb_team_member name=\u00bbThomas Ebensen\u00bb position=\u00bbCient\u00edfic s\u00e8nior\u00bb image_url=\u00bbhttps:\/\/www.thervacb.eu\/wp-content\/uploads\/hzi-thomas-ebensen.jpg\u00bb _builder_version=\u00bb4.16&#8243; header_text_align=\u00bbcenter\u00bb position_text_align=\u00bbcenter\u00bb position_line_height=\u00bb2em\u00bb text_orientation=\u00bbleft\u00bb custom_padding=\u00bb20px|20px|20px|20px|false|false\u00bb border_radii=\u00bbon|10px|10px|10px|10px\u00bb box_shadow_style=\u00bbpreset1&#8243; global_colors_info=\u00bb{}\u00bb transform_styles__hover_enabled=\u00bbon|hover\u00bb transform_scale__hover_enabled=\u00bbon|hover\u00bb transform_translate__hover_enabled=\u00bbon|desktop\u00bb transform_rotate__hover_enabled=\u00bbon|desktop\u00bb transform_skew__hover_enabled=\u00bbon|desktop\u00bb transform_origin__hover_enabled=\u00bbon|desktop\u00bb transform_scale__hover=\u00bb105%|105%\u00bb custom_css_member_image_last_edited=\u00bbon|desktop\u00bb]<\/p>\n<p style=\"text-align: center;\">Gesti\u00f3 cient\u00edfica, <br \/>Vacunologia i Immunologia<\/p>\n<p>[\/et_pb_team_member][\/et_pb_column][et_pb_column type=\u00bb1_3&#8243; _builder_version=\u00bb4.16&#8243; global_colors_info=\u00bb{}\u00bb][et_pb_team_member name=\u00bbBlair Prochnow\u00bb position=\u00bbCap de projecte\u00bb image_url=\u00bbhttps:\/\/www.thervacb.eu\/wp-content\/uploads\/hzi-blair-prochnow.jpg\u00bb _builder_version=\u00bb4.16&#8243; header_text_align=\u00bbcenter\u00bb position_text_align=\u00bbcenter\u00bb position_line_height=\u00bb2em\u00bb text_orientation=\u00bbleft\u00bb custom_padding=\u00bb20px|20px|20px|20px|false|false\u00bb border_radii=\u00bbon|10px|10px|10px|10px\u00bb box_shadow_style=\u00bbpreset1&#8243; global_colors_info=\u00bb{}\u00bb transform_styles__hover_enabled=\u00bbon|hover\u00bb transform_scale__hover_enabled=\u00bbon|hover\u00bb transform_translate__hover_enabled=\u00bbon|desktop\u00bb transform_rotate__hover_enabled=\u00bbon|desktop\u00bb transform_skew__hover_enabled=\u00bbon|desktop\u00bb transform_origin__hover_enabled=\u00bbon|desktop\u00bb transform_scale__hover=\u00bb105%|105%\u00bb custom_css_member_image_last_edited=\u00bbon|desktop\u00bb]<\/p>\n<p style=\"text-align: center;\">Gesti\u00f3 de projectes<\/p>\n<p>[\/et_pb_team_member][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Helmholtz-Zentrum f\u00fcr Infektionsforschung GmbH (HZI) Informaci\u00f3 general El Helmholtz Center for Infection Research (HZI) de Braunschweig \u00e9s un centre d&#8217;investigaci\u00f3 finan\u00e7at amb fons p\u00fablics amb m\u00e9s de 900 empleats i un pressupost anual d&#8217;aproximadament 70 milions d&#8217;euros, aix\u00ed com fons externs d&#8217;aproximadament 16 milions d&#8217;euros procedents de programes de suport nacionals i internacionals i de [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":3533,"menu_order":8,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_monsterinsights_skip_tracking":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-3676","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.4 - aioseo.com -->\n\t<meta name=\"description\" content=\"HZI aporta c-di-AMP al projecte TherVacB i proporciona la seva experi\u00e8ncia en 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