{"id":11428,"date":"2024-05-28T11:28:15","date_gmt":"2024-05-28T10:28:15","guid":{"rendered":"https:\/\/www.thervacb.eu\/?p=11428"},"modified":"2025-06-16T10:41:39","modified_gmt":"2025-06-16T09:41:39","slug":"ip-cure-b-thervacb-workshop-no2","status":"publish","type":"post","link":"https:\/\/www.thervacb.eu\/ca\/ip-cure-b-thervacb-workshop-no2\/","title":{"rendered":"Researchers from \u201cIP-cure-B\u201d &#038; \u201cTherVacB\u201d continue the dialogue to advance elimination of chronic hepatitis B"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.25.0&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Researchers from the two EC-funded projects\u00a0 <a href=\"https:\/\/ipcureb.eu\/\" target=\"_blank\" rel=\"noopener\" title=\"IP-cure-B website\">\u2018IP-cure-B \u2013 Take care of your health\u2019<\/a> and <a href=\"https:\/\/www.thervacb.eu\/the-project\/\" target=\"_blank\" rel=\"noopener\" title=\"TherVacB project \">\u2018TherVacB &#8211; A therapeutic vaccine to cure Hepatitis B\u2019 <\/a>continue their collaboration to jointly tackle some of the major challenges in the therapy of viral hepatitis.<\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.25.0&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Building on a first exploratory session in summer 2023, a wider team of researchers are meeting on 5<sup>th<\/sup> June 2024 for a 2<sup>nd<\/sup> round of strategic discussions. The workshop is hosted by both consortia at <a href=\"https:\/\/www.easlcongress.eu\/\" target=\"_blank\" rel=\"noopener\">the Congress of the European Association for the Study of the Liver (EASL) 2024 in Milano, Italy,<\/a> and held at the Milano Convention Centre \u201cAllianz MiCo\u201d in the South Wing Level 2 meeting room \u201cAmber 6\u201d.\u00a0<\/p>\n<h3><\/h3>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Turquoise box&#8221; module_class=&#8221;whitelink&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; header_3_text_color=&#8221;#FFFFFF&#8221; header_4_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#ce2525&#8243; custom_padding=&#8221;30px|30px|30px|30px|true|true&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2><strong>Different approaches, a common goal<br \/><\/strong><\/h2>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.21.0&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>In 2020, work on chronic hepatitis B by the research and clinical communities in the two projects had kicked-off in parallel. Funded by the <a href=\"https:\/\/cordis.europa.eu\/search?q=contenttype%3D%27project%27%20AND%20programme%2Fcode%3D%27SC1-BHC-14-2019%27&amp;p=1&amp;num=10&amp;srt=\/project\/contentUpdateDate:decreasing\">European Commission under the same topic<\/a>, both research teams have adopted stratified host-directed approaches to raise awareness and improve prevention, treatment and functional cure of hepatitis B.\u00a0\u00a0<\/p>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;Turquoise box&#8221; module_class=&#8221;whitelink&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; header_3_text_color=&#8221;#FFFFFF&#8221; header_4_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#ce2525&#8243; custom_padding=&#8221;30px|30px|30px|30px|true|true&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2><strong>Focussed strategy discussions to create synergies<\/strong><strong><\/strong><\/h2>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.21.0&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; custom_padding=&#8221;0px|||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>At EASL 2024, a larger group of <a href=\"https:\/\/ipcureb.eu\/strategy\/%20\">IP-cure-B<\/a> and <a href=\"https:\/\/www.thervacb.eu\/the-project\/%20\">TherVacB experts<\/a> in virology, immunology and clinical hepatitis will engage in focused discussions on the different aspects of viral hepatitis B infection (HBV) and the HBV-mediated chronic disease that they are investigating to reduce the global health burden:\u00a0<\/p>\n<ul>\n<li>the therapeutic approaches,<\/li>\n<li>the clinical trials,<\/li>\n<li>virologic monitoring, immune profiling and biomarker identification &amp;<\/li>\n<li>the TherVacB Patient Registry.<\/li>\n<\/ul>\n<p>[\/et_pb_text][et_pb_cta title=&#8221;Follow our journeys&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#706F6F&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span style=\"color: #000000;\"><span style=\"color: #ffffff;\">Stay tuned on Twitter at <a href=\"https:\/\/twitter.com\/ipcureb\" target=\"_blank\" rel=\"noopener\" title=\"IP-cure-B Twitter channel\" style=\"color: #ffffff;\"><strong>@ipcureb<\/strong><\/a> and at <a href=\"https:\/\/twitter.com\/thervacb_eu?lang=en\" target=\"_blank\" rel=\"noopener\" title=\"TherVacB Twitter Channel\" style=\"color: #ffffff;\"><strong>@TherVacB_EU<\/strong><\/a>. Learn more on the European Commission\u2019s regularly updated Project Pages for <span style=\"text-decoration: underline;\"><a href=\"https:\/\/cordis.europa.eu\/project\/id\/848223\" target=\"_blank\" rel=\"noopener\" title=\"EC&#039;s Project Page for TherVacB\" style=\"color: #ffffff; text-decoration: underline;\">TherVacB<\/a><\/span> and <a href=\"https:\/\/cordis.europa.eu\/project\/id\/847939\" target=\"_blank\" rel=\"noopener\" title=\"EC's Project Page for IP-cure-B\" style=\"color: #ffffff;\"><span style=\"text-decoration: underline;\">IP-cure-B<\/span><\/a>. <\/span><br \/><\/span><\/p>\n<p>[\/et_pb_cta][et_pb_text admin_label=&#8221;Turquoise box&#8221; module_class=&#8221;whitelink&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; header_3_text_color=&#8221;#FFFFFF&#8221; header_4_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#FFFFFF&#8221; width=&#8221;100%&#8221; custom_padding=&#8221;30px|30px|30px|30px|true|true&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><strong><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.thervacb.eu\/wp-content\/uploads\/eu-flag-logo.jpg\" width=\"59\" height=\"39\" alt=\"\" class=\"wp-image-63 alignleft size-full\" \/><\/strong><span style=\"color: #ffffff;\"><span style=\"color: #000000;\"> TherVacB and IP-cure-B research projects have received funding from the EU&#8217;s H2020 RIA programme (GA no. 848223 and 847939).<\/span><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers from the two EC-funded projects\u00a0 \u2018IP-cure-B \u2013 Take care of your health\u2019 and \u2018TherVacB &#8211; A therapeutic vaccine to cure Hepatitis B\u2019 continue their collaboration to jointly tackle some of the major challenges in the therapy of viral hepatitis.Building on a first exploratory session in summer 2023, a wider team of researchers are meeting [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":11697,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<h3>Experts in virology, immunology and clinical hepatitis from \u2018IP-cure-B \u2013 Take care of your health\u2019 and \u2018TherVacB - A therapeutic vaccine to cure Hepatitis B\u2019 research projects are working towards to cure hepatitis B.<\/h3><p>To jointly tackle some of the major challenges in the therapy of viral hepatitis, researchers have met for a first round of strategic discussions in July 2023.<\/p><h3><strong>Common goal to improve the cure rate of HBV and CHB <\/strong><\/h3><p>To achieve functional cure, the research projects investigate different aspects of viral hepatitis B infection (HBV) and the HBV-mediated chronic disease.<\/p><p>IP-cure-B aims to improve the cure rate in patients with chronic hepatitis B (CHB) with complementary immunomodulatory concepts. Immune interventions are investigated in two settings, in a pre-clinical model and a proof-of-concept clinical study. IP-cure-B innovations in immunotherapy will boost strategic selection of the best combination for effective treatment in future clinical studies.<\/p><p>TherVacB provides a novel curative treatment option that aims to break immune tolerance in chronic HBV infection and allow the immune system to clear the virus. Novel TherVacB vaccine components will be tested in patients with CHB in a multicentre clinical proof-of-concept study. Finally, TherVacB aims to provide a novel and affordable, safe and well tolerable curative treatment option for CHB and a first opportunity for patients in Tanzania to be treated for hepatitis B.<\/p><h3><strong>Contribute to the UN\u2019s Strategic Development Goals for sustained health in endemic countries<\/strong><\/h3><p>The innovations from IP-cure-B and TherVacB will be instrumental to meeting the UN\u2019s Sustainable Development Goal 3:<\/p><ul><li>combat hepatitis B (and D) viral infection worldwide by the year 2023,<\/li><li>ensure sustained health, increase the quality of life and stop stigmatization<\/li><li>including in highly endemic countries that cannot afford lifelong therapies and their monitoring.<\/li><\/ul><p>\u00a0<\/p><p>TherVacB and IP-cure-B research projects have received funding from the EU's H2020 RIA programme (GA no. 848223 and 847939). Learn more on the European Commission\u2019s regularly updated Project Pages for TherVacB and IP-cure-B. Follow the journeys of IP-cure-B on Twitter @ipcureb and of TherVacB on Twitter @TherVacB_EU.<\/p><p>\u00a0<\/p><p>\u00a0<\/p><p>\u00a0<\/p>","_et_gb_content_width":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[58,16,1,18,13,17,15,14],"tags":[],"class_list":["post-11428","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-events","category-nachrichten","category-news","category-noticias","category-noticies","category-notizia","category-nouvelles","category-14"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.thervacb.eu\/ca\/wp-json\/wp\/v2\/posts\/11428","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.thervacb.eu\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.thervacb.eu\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.thervacb.eu\/ca\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.thervacb.eu\/ca\/wp-json\/wp\/v2\/comments?post=11428"}],"version-history":[{"count":11,"href":"https:\/\/www.thervacb.eu\/ca\/wp-json\/wp\/v2\/posts\/11428\/revisions"}],"predecessor-version":[{"id":12547,"href":"https:\/\/www.thervacb.eu\/ca\/wp-json\/wp\/v2\/posts\/11428\/revisions\/12547"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.thervacb.eu\/ca\/wp-json\/wp\/v2\/media\/11697"}],"wp:attachment":[{"href":"https:\/\/www.thervacb.eu\/ca\/wp-json\/wp\/v2\/media?parent=11428"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.thervacb.eu\/ca\/wp-json\/wp\/v2\/categories?post=11428"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.thervacb.eu\/ca\/wp-json\/wp\/v2\/tags?post=11428"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}