TherVacB – A THERAPEUTIC VACCINE TO CURE HEPATITIS B
European Commission and TherVacB join forces
The role of viral hepatitis as a public health threat has long been underestimated. Only very recently, the United Nations in their “2030 Agenda for Sustainable Development” called for international action to combat viral hepatitis and reduce the disease burden. The major killer is the hepatitis B virus (HBV) causing liver cirrhosis and liver cancer. Worldwide 880,000 humans die each year from the consequences of an HBV infection.
A prophylactic vaccine is available to prevent HBV infection, but more than 3% of the world’s population (about 260 million humans) are chronically infected and do not profit from that vaccine anymore. For those suffering from chronic hepatitis B, until today no curative treatment option exists.
The European Commission therefore selected the project TherVacB led by Helmholtz Zentrum München for a seven-year funding within the Horizon 2020 program.
A consortium of leading virologists, immunologists and physicians specialized in treating viral hepatitis, will use a newly designed therapeutic vaccine, TherVacB, as an immunotherapy to cure HBV. TherVacB will be evaluated in a clinical trial starting in January 2025 conducted in Europe and in Africa. Integration of a partner site in Tanzania shall help building local capacities for diagnosing and treating hepatitis B and support an important goal of the consortium – to raise awareness for hepatitis B.
About TherVacB
For Patients
TherVacB Team
Partners
European countries
months project duration
It’s time for action, it’s World Hepatitis Day 2024!
Every year, 1.3 million people lose their lives to hepatitis. New data from the World Health Organization shows the number of deaths is rising. The TherVacB team is not waiting for change. Together with researchers from the D-Solve consortium and supporting partners,...
Researchers from “IP-cure-B” & “TherVacB” continue the dialogue to advance elimination of chronic hepatitis B
Researchers from the two EC-funded projects ‘IP-cure-B – Take care of your health’ and ‘TherVacB - A therapeutic vaccine to cure Hepatitis B’ continue their collaboration to jointly tackle some of the major challenges in the therapy of viral hepatitis.Building on a...
Bavarian Award ‘m4’ honours the TherVacB innovative therapeutic vaccine as a promising solution to the global health challenge of chronic hepatitis B
Professor Ulrike Protzer and her TherVacB team at Helmholtz Munich and TUM have been honoured with the prestigious Bavarian m4 Award 2023. Key members of the Helmholtz Munich and TUM team for TherVacB proudly received the m4 Award on 24 October 2023 at Munich...
Animation movie
Enjoy our animation movie to understand the mission and approach of the TherVacB project!
TherVacB Publications
Find here scientific publications and technical articles from TherVacB project partners.
Read more about chronic hepatitis B, the virus, screening and testing for hepatitis C and B, therapeutic vaccination, and cure research.
All you need to know to understand Hepatitis B cure research – The HBV Cure FAQs
Watch the growing collection of short videos answering key questions on cure research raised by people living with Hepatitis B (HBV). The collection is a product of an international consortium of organizations, expert institutions and research projects working in and around Hepatitis B. Actively involved are ICE-HBV, Hepatitis B Foundation, World Hepatitis Alliance, HepBCommunity.org, Australian Centre for Hepatitis Virology, IP-cure-B, the Canadian HBV Network and TherVacB.
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🤔Wie wird die #HepD behandelt? Warum ist dies für #HepB-Betroffene relevant? 🇩🇪🗺️
🎞️Einblicke von #MHH Internistinnen🥼@hkefalakes & #LisaSandmann jetzt im neuen Video
📺 #HepatitisAwareness mit Expert*innen zu #HBV & #HDV
@No_hep @DSOLVE_EU #B_Aware
📢Latest #BLOG: New AGA Guidelines on Hepatitis B Reactivation!
The American Gastroenterological Association (AGA) has released updated guidelines to prevent and manage #hepatitisB reactivation (HBVr) in at-risk individuals. #HBV #hepB
Read more📲 https://ow.ly/NaY050V2WHb
Training frontline healthcare workers is an essential part of our funding model, ensuring that every dollar has the greatest impact—protecting newborns from #hepatitis B and bringing us closer to elimination.
Frontline heroes like Claudine are making this vision a reality.👏
🗞 This month’s top highlight: @AfricaCDC is investing $1.6M to strengthen public health institutes across Africa.
Nine newly designated National Public Health Institutes will serve as regional Centers of Excellence, providing peer-to-peer technical assistance, training, and…