TherVacB – A THERAPEUTIC VACCINE TO CURE HEPATITIS B
European Commission and TherVacB join forces
The role of viral hepatitis as a public health threat has long been underestimated. Only very recently, the United Nations in their “2030 Agenda for Sustainable Development” called for international action to combat viral hepatitis and reduce the disease burden. The major killer is the hepatitis B virus (HBV) causing liver cirrhosis and liver cancer. Worldwide 880,000 humans die each year from the consequences of an HBV infection.
A prophylactic vaccine is available to prevent HBV infection, but more than 3% of the world’s population (about 260 million humans) are chronically infected and do not profit from that vaccine anymore. For those suffering from chronic hepatitis B, until today no curative treatment option exists.
The European Commission therefore selected the project TherVacB led by Helmholtz Zentrum München for a five-year funding within the Horizon 2020 program.
A consortium of leading virologists, immunologists and physicians specialized in treating viral hepatitis, will use a newly designed therapeutic vaccine, TherVacB, as an immunotherapy to cure HBV. TherVacB will be evaluated in a three-year clinical trial starting in 2022 conducted in Europe and in Africa. Integration of a partner site in Tanzania shall help building local capacities for diagnosing and treating hepatitis B and support an important goal of the consortium – to raise awareness for hepatitis B.
About TherVacB
For Patients
TherVacB Team
Partners
European countries
Project duration (months)
European Testing Week 15-22 May 2020
European Testing Week 2020 aims to increase testing efforts & promote awareness on the benefits of hepatitis/HIV testing! More details here.
World Hepatitis Day 28th July 2020!
Keep in mind! World Hepatitis Day (WHD) takes places every year on 28 July bringing the world together under a single theme to raise awareness of the global burden of viral hepatitis and to influence real change. Read more
The official kick-off meeting for TherVacB was held online!
Thanks to all TherVacB partners for taking time and for great discussions on how to cure hepatitis B patients!
Animation movie
Enjoy our animation movie to understand the mission and approach of the TherVacB project!
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Check out the new #HBV #research protocol on #ICEHBV website: Fluorescent-bait labelling for the ex vivo detection of HBV antigen-specific B cells. Thank you to authors @bertoletti_lab @Anto_Berto @maini_lab and to our great project leader @haitao_guo ! #NoHep #HBVcure
"Knowing that both my children were properly immunised against #hepatitis B at birth gave me great
confidence that they would be free of hepatitis B."
Read Michelle's story about breaking the cycle of mother-to-child transmission in this month's hepVoice: https://www.worldhepatitisalliance.org/hepvoice
Ending mother-to-child transmission is key to #hepatitis elimination. Join the #NOhep Moms a new @NO_hep campaign calling for testing of ALL pregnant women, linking them to care and vaccinating their babies to #eliminate hepatitis!
Learn more and join: https://www.nohep.org/moms/
Today is World Liver Day! #Hepatitis B is the most serious liver disease globally. Know your risks and get screened for #hepB today. #WorldLiverDay #HBV #hepatitisB http://www.hepb.org
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 848223.