The HBV Cure FAQs

All you need to know to understand Hepatitis B cure research

Collection of HBV Cure FAQ videos

Community webinars about Hepatits B cure (HBV) have been taking place the past few years with ICE-HBV and partners from around the world, aimed at empowering the community by equipping them with the knowledge needed to understand the HBV cure research that is taking place for their benefit. Based on this idea, a group of international organizations, expert institutions and research projects working in and around Hepatitis B, including TherVacB, are partnering to create an enduring tool for people to understand the cure research: the HBV Cure FAQs. This growing collection of short videos answers key questions to HBV cure research raised by people living with Hepatitis.

Find all HBV Cure FAQ videos here.

Why do we need a Hepatitis B cure?

People living with Hepatitis B in Nigeria, Africa and all over the world need a cure to have hope for the future, to be able to stop the struggling, stop the fear of transmitting the virus, to remove shame and stigma and be confident every day.

Answered by: Danjuma Adda, Nigeria

President, World Hepatitis Alliance

What do you mean by a Hepatitis B cure?

The nature of the Hepatitis B virus is complex and can cause different kinds of infection. Thus, there are actually four levels of cure, each building on top of the last: level I partial cure, level II functional cure, level III complete cure and level IV sterilizing cure.

Answered by: Thomas Tu, Australia

Founder and Director, HepBCommunity.org; President, Australian Centre for Hepatitis Virology; Group Leader, Westmead Institute for Medical Research, University of Sydney, Australia

What could a Hepatitis B cure look like?

How are current therapies working and why is a functional cure of Hepatitis B so hard? Combination therapy with different drugs is the way to go to treat patients … but what tools do we think we will have to cure HBV?

Answered by: John Tavis, USA

Professor of Virology,St. Louis University School of Medicine, USA; Director, St. Louis University Drug Discovery Institute; Incoming Chair, International Coalition to Eliminate HBV ICE-HBV

Clinical Trials: Why do we need them?

Why do we need clinical trials for HBV? And what does Phase 1, 2, and 3 mean?

Answered by: Philippa Matthews, UK

Infection Doctor and Clinical Group Leader at The Francis Crick Institute, UK

What do we need to achieve an HBV cure?

What do you think we are going to need to achieve an HBV cure? Anti-virals, immune therapies, or both?

Answered by: Ulrike Protzer, Germany

Institute of Virology, Technical University Munich / Helmholtz Munich, Germany - Coordinator of TherVacB

How possible is a cure for Hepatitis B?

Is a cure for HBV possible in the near future? Which therapeutic concepts are considered by the HBV cure research community in HBV treatment? Which are the main questions dealt with in clinical trials working to achieve functional HBV cure?

Answered by: Fabien Zoulim, France

ICE-HBV Chair, Medical Director of the Hepatology Department at the Hospices Civils de Lyon, and Scientific Director of the Department of Immunology and Virology of INSERM Unit 1052, France