| Title | Address | Description |
|---|---|---|
LMU | GESCHWISTER SCHOLL PLATZ 1, 80539 München, |
|
Fundació Clínic per a la Recerca Biomèdica | Carrer del Rosselló, 149, 08036 Barcelona, Spanien |
|
Helmholtz-Zentrum für Infektionsforschung GmbH (HZI) | Ingolstädter Landstraße 1, 85764 Oberschleißheim, Deutschland |
|
Helmholtz ZentrumfürInfektionsforschung GmbH | Inhoffenstraße 7, 38124 Braunschweig, Deutschland |  |
Medizinische Hochschule Hannover | Carl-Neuberg-Straße 1, 30625 Hannover, Deutschland |
|
NIMR-Mbeya Medical Research Center | Hospital Hill Rd, Mbeya, Tansania |
|
Technische Universität München | Arcisstraße 21, 80333 München, Deutschland |
|
UNIVERSITY COLLEGE LONDON (UCL) | GOWER STREET, WC1E 6BT London |
|
Klinikum Rechts der Isar der Technischen Universität München | Hörsaal A, Klinikum rechts der Isar, Ismaninger Str. 22, 81675 München, Deutschland |
|
University Medical Center Hamburg-Eppendorf, I. Department of Internal Medicine | Martinistraße 52, 20251 Hamburg, Deutschland |
|
Azienda Ospedaliero- Universitaria di Parma | Str. dell'Università, 12, 43121 Parma PR, Italien |  |
Universität Leipzig | Ritterstraße 26, 04109 Leipzig, Deutschland |
|
Barts Health NHS Trust | Co-operative Bank Plc, 9 Prescot St, Whitechapel, London E1 8AZ, Vereinigtes Königreich |
|
Royal Free London NHS Foundation Trust | Pond St, Hampstead, London NW3 2QG, Vereinigtes Königreich | |
ARTTIC Innovation GmbH | Oskar-von-Miller-Ring 29, 80333 München, Germany |
|
MONIPOL - Clinical Research | Roncallistraße 39, 53123 Bonn, Germany |
|
NIMR-Mbeya Medical Research Center
General Information
The NIMR is one of the eight medical research centres of the National Institute for Medical Research (NIMR) in Tanzania, eastern Africa. It is the largest public health research institution in the country, established by the Parliamentary Act No. 23 of 1979 as a parastatal organization of the Government of the United Republic of Tanzania under the Ministry of Health Community Development Gender, Elderly and Children (MoHCDGEC). The establishment of NIMR reflects the government’s recognition of the need to generate scientific information required in the development of better methods and techniques of enhancing disease management, prevention and control in the country. NIMR is headed by the Director General and has a governing council with its chairperson being a presidential appointee.
The Mbeya Medical Research Center (MMRC) of the NIMR is located in the Southern Highlands zone of Tanzania, with about 157 employees. The MMRC has grown to become a centre of excellence for conducting operational research in TB and HIV, GCPcompliant phase I to III clinical trials basic research and strong social science progammes.
Role in TherVacB
NIMR-MMRC will provide capacity building for the Tanzanian partner site specific to the conduct of hepatitis B related trial performance. NIMR MMRC will quantitatively determine the key secondary immunological endpoints within the African study arm to provide evidence for overall success of therapeutic vaccination and for successful target engagement (reduction in key viral parameters and induction of HBV-specific humoral and T cell immune).
Project Staff
Lucas Maganga
Head of Department HIV and Reproductive Health
He is a senior scientist since 2006 and has been PI for many HIV research projects including international multicenter phase I/IIb studies. In TherVacB, NIMR will establish a patient cohort and Lucas will serve as local PI for the clinical trial.
Marco Missanga
Clinician - Internal Medicine Specialist
He is an internal medicine specialist and senior research scientist. He started his research career in 2010 as a junior scientist, later to become a CRC and co-PI in Phase I/II HIV vaccine trials. He possess vast experience in coordinating highly regulated trials and in TherVacB he will serve as a co- PI.
Wiston William
Head of “Epidemiology and Operational Research” Unit
He began his career in research in 2011 as study clinician in HIV cohort studies at MMRC and then joined HIV Vaccine Trials in 2016 as PI in two ongoing multinational HIV Vaccine Trials.
Emmanuel Kapesa
Head of Unit Clinical Trial - Clinician
He is a study physician and research scientist. He started his research career in 2013 as a junior research scientist, later to become a CRC in Phase I/IIb HIV vaccine trials. He possess vast experience in coordinating highly regulated trials.
Faith Mlagalila
Clinician
She is a study physician and research scientist. She started her research career in 2015 as a junior research scientist, worked under supervision of experienced scientists to become independed physician able to confidently execute trial related procedures for phase I/IIb.
Joel Mwakisisile
Clinician
He is a study physician and senior research scientist. He started his research career in 2008 as a junior research scientist. He possess vast experience in coordinating highly regulated trials.
Amani Kway
Clinician
He is a study physician and research scientist. He started his research career in 2017 as a junior research scientist, he is working under supervision of experienced scientists and he is participating in the conduct of ongoing HIV high risk cohort and phase IIb studies.