Title	Address	Description
LMU	GESCHWISTER SCHOLL PLATZ 1, 80539 München,
Fundació Clínic per a la Recerca Biomèdica	Carrer del Rosselló, 149, 08036 Barcelona, Spanien
Helmholtz-Zentrum für Infektionsforschung GmbH (HZI)	Ingolstädter Landstraße 1, 85764 Oberschleißheim, Deutschland
Helmholtz Munich	Inhoffenstraße 7, 38124 Braunschweig, Deutschland
Medizinische Hochschule Hannover	Carl-Neuberg-Straße 1, 30625 Hannover, Deutschland
NIMR-Mbeya Medizinisches Forschungszentrum	Hospital Hill Rd, Mbeya, Tansania
Technische Universität München	Arcisstraße 21, 80333 München, Deutschland
UNIVERSITY COLLEGE LONDON (UCL)	GOWER STREET, WC1E 6BT London
Klinikum Rechts der Isar der Technischen Universität München	Hörsaal A, Klinikum rechts der Isar, Ismaninger Str. 22, 81675 München, Deutschland
UKE Hamburg Eppendorf	Martinistraße 52, 20251 Hamburg, Deutschland
Azienda Ospedaliero- Universitaria di Parma	Str. dell'Università, 12, 43121 Parma PR, Italien
Universitätsklinikum Leipzig	Ritterstraße 26, 04109 Leipzig, Deutschland
Barts Health NHS Trust	Co-operative Bank Plc, 9 Prescot St, Whitechapel, London E1 8AZ, Vereinigtes Königreich
Royal Free London NHS Foundation Trust	Pond St, Hampstead, London NW3 2QG, Vereinigtes Königreich
PNO Innovation GmbH	Oskar-von-Miller-Ring 29, 80333 München, Germany
SocraTec R&D GmbH	Im Setzling 35, 61440 Oberursel (Taunus), Deutschland
Universitätsklinikum Frankfurt	Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Deutschland

Universität Leipzig

General Information

The Department of Hepatology of the University of Leipzig (ULEI) represents one of the largest hepatology units in Germany. It includes several specialized outpatient clinics with yearly presentation of > 5.000 patients, covering the whole spectrum of hepatology, hepatologic oncology and liver transplantation, a large study office with 5 full time study nurses and a research laboratory. Clinical trials are being or have been conducted ranging from phase I-IV with special focus on hepatitis B, hepatitis C, hepatocellular carcinoma, fatty liver diseases (NASH, NAFLD) and other liver diseases.
The research laboratory of the Department of Hepatology conducts numerous clinical studies as well as basic and translational scientific projects including the fields of viral hepatitis, hepatocellular carcinoma, human microbiome and genomics in hepatology. Multiple national and international cohort studies have been initiated from the section of hepatology. Every year, high ranking publications underline the strong scientific impact of the unit.

Universität Leipzig
Klinik und Poliklinik für Onkologie, Gastroenterologie, Hepatologie, Pneumologie, Infektiologie

Liebigstr. 20
04103 Leipzig
Germany
link

Role in TherVacB

ULEI has long term experience in conducting clinical trials (phase I-IV), appropriate facilities and a well-trained staff. The university is currently involved in several translational studies and has great experience with the collection of patient materials. This includes serum, tissue and circulating blood cell (PBMC) samples, which can be collected and stored according to highest quality requirements. A special focus lies on the development of bio markers for hepatitis B virus infections. The Department of Hepatology has gained significant international reputation in the field and will contribute experience and methodology to the consortium.

ULEI has a large international network with collaborating hospitals and residents and can mobilize significant patient populations for inclusion in the clinical trials. Its experience is especially great in studies in hepatitis B, as well as in vaccine trials.